The negative pressure isolator is a sealed protective device specially designed for high-risk biological environments. It actively creates a negative-pressure internal environment to fundamentally block the spread of pathogenic microorganisms, building an impenetrable safety barrier for medical staff, laboratory personnel and the surrounding environment. Its core principle is to use a dedicated ventilation system to keep the air pressure inside the isolation chamber lower than that of the external environment. Air flows only in one direction into the chamber, and contaminated air inside the chamber can only be exhausted after high-efficiency filtration (HEPA filtration efficiency ≥99.995%), eliminating the risk of cross-infection.

Generally, it consists of an operation chamber, continuous bag-out system, RTP valve system, control system, cleaning system, sterilization system, waste liquid collection module and other components. Users may configure functions according to process requirements. It is mainly used in operational processes that are toxic and polluting to humans or the environment, and is widely applied especially in industries such as anti-tumor drugs, active biological products and animal testing.

Negative-pressure isolators are widely used in the medical field and other industrial environments requiring a high degree of cleanliness. For example, in the treatment and patient care of infectious diseases, negative-pressure isolators are applied for patient isolation and air filtration to prevent the transmission of viruses and bacteria within medical institutions. When high-risk surgical procedures such as tracheal intubation, artificial ventilation and sputum suction need to be performed in hospitals, medical staff may transfer infected patients to negative-pressure isolation rooms. This protects medical workers while safeguarding the health of other patients and preventing virus spread and cross-infection.

In addition, negative-pressure isolators are also extensively adopted in industrial sectors including chemistry, food and pharmaceuticals. In the pharmaceutical industry, negative-pressure isolators are used during drug preparation to protect researchers, laboratory environments and pharmaceutical equipment, thus reducing impacts on the structure and quality of medicines.

An isolation system is an air purification product that separates operators from powdered or liquid products in laboratory or production processes by means of physical barriers. Its main principle is to isolate animals or articles inside the isolator from the external environment from a microbiological perspective. Air is delivered by a supply fan, filtered through air filters and then fed into the isolator. The isolator is fitted with rubber gloves, through which all internal operations inside the isolator are carried out. Isolators generally adopt the form of a sealed cabinet. Based on the air pressure difference between the interior of the isolator and the outside world, isolators are divided into two major categories: positive-pressure isolators and negative-pressure isolators. Its exhaust system must be equipped with high-efficiency air filters, with an exhaust fan installed downstream. Negative-pressure isolators are usually fitted with one-way exhaust valves to prevent backflow when air inside the isolator is discharged outward.

·The negative pressure isolator can ensure that harmful toxic substances in

the operation cabin do not leak outside the cabin.

·The negative pressure isolator can automatically adjust the negative pressure inside the cabin according to the set value and has an emergency response function.Once the isolator detects internal pressure loss or leakage,it will automatically respond and adjust to ensure that the air flow of the isolator enters

from the background room,thus avoiding the spread of toxic substances.

·It has a reasonable and compact structure,offering  high cost-effectiveness.

·It can be equipped with a disinfection and inactivation treatment system to achieve disinfection effects.

·It can be configured with a waste liquid collection module with a breathing function

  to prevent the escape of toxic substances and environmental pollution.

·The exhausted air undergoes double -layer filtration protection,enhancing the safety of the exhausted air.